Desperados 2: Cooper's RevengeDesperados 2: Cooper's Revenge - Internet Movie Firearms Database - Guns in Movies, TV and Video GamesDesperados 2: Cooper's Revenge
Note: games "Desperados: Wanted Dead Or Alive", "Desperados 2: Cooper's Revenge" and "Desperados 3: Helldorado" have the same weapon, also there is the same 3D models in "Desperados 2" and "Desperados 3", so I used some Desperados 3 wallpapers and screenshots.
Remington 1875 is a primary handgun of Desperados games. It's using by most enemies and also by John Cooper and Doc McCoy. One accurate shot is always killing enemy.
Doc McCoy uses the modified Remington 1875 with long barrel. It also can be used with an optical sight and stock. Doc fires much slower than Cooper (Doc is coking hammer by his finger, Cooper - by left hand).
The Winchester rifle in game look very similar to the Winchester Model 1873. It's using by many enemies and by Sam Williams. In Sam's hand it's not very good weapon: it's weak, have a handgun range of fire and very seldom killing enemy with one hit (even in head!). It's useful only in close range, so it must be done like a shotgun, not a rifle.
Kate O'Hara uses unknown/fiction three-barreled pistol. The pistol is very weak and you can kill only one enemy without reloading. But this is a self-defence weapon, using by Kate when her tricks is fail.